81377 München christian.haass(at)dzne.de +49 89 4400-46549 Areas of investigation/research focus Prof. Haass started to work on Alzheimer's disease (AD) hinein 1990 at a time, when very little was known about the cellular mechanisms involved. Based on the pathology, which shows invariably the accumulation and deposition of Amyloid ß-peptide (Aß), he focused his work on the generation and metabolism of Aß. Christian Haass hypothesized against the widely accepted general opinion in this field that Aß may be produced from its precursor rein a physiologically normal pathway and not necessarily in a pathological process. Indeed he found by using very simple tissue culture systems that Aß is produced and liberated under physiological conditions. This pivotal finding welches a major breakthrough for the entire field, since it allowed elucidating the molecular principles behind Aß generation as well as the identification of the enzymes (the so-called secretases) involved hinein generation and liberation of the peptide and finally the development of selective inhibitors to therapeutically lower Aß production in patients.
On this page you will find all the information you need again in Baustein; from there you can also fix an appointment online with your local citizen’s office.
Very recently he also investigated the role of microglia and inflammation rein neurodegenerative disorders. This work led to the spectacular finding that microglial phagocytosis may be impaired late during neurodegeneration and opened up a completely unexpected road towards new therapeutic developments for patients already developing disease symptoms. This work resulted hinein the identification of TREM2 as a CSF marker for microglial activity. In a unique cohort of subjects with autosomal dominant AD, CSF sTREM2 was abnormally increased 5 years before the expected onset of symptoms. This will not only greatly facilitate research on inflammatory disease overarching mechanisms, but may also provide a very valuable therapeutic marker.
Yes, you can, but the Weiterbildung contract only becomes valid when it is signed by your father or mother.
The practical side is taken care of in ur top-notch driving-school vehicles, each equipped with a double-pedal Gebilde. If requested, we can also provide you with tuition rein an automatic car at ur driving school hinein Munich.
As ur driving instructors receive ongoing further Weiterbildung, they are rein a position to inform you on all the latest road traffic requirements. For easier comprehension during practical Fortbildung, we have instructors that speak not only German but also English, Persian and Greek.
My first driving lesson will take place in the winter when it is already dark. Does that count as night-driving? No. Your driving instructor is only allowed to give lessons hinein special driving situations towards the end of Weiterbildung (when you have acquired the necessary knowledge; but your first driving lesson with us will never take place at this time of the day!).
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Refresher driving lessons COURSES Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua
We will give you driving lessons designed to suit your own particular needs not only during the week but also on Saturdays. In this way you will get your driving licence as quickly as possible.
einer elektrischen Antriebsmaschine oder einem Verbrennungsmotor mit einem Hubraum von nicht etliche denn 50 cm³ oder
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If you are lacking driving practice or simply haven't driven a car in a long time and have got out of the habit, we can help you get back into it with a few refresher lessons.
Yes, a trial lesson is always possible and of course free of Lot; if you decide to register with us, this trial lesson will be credited to you as "attended". I would like to register at Momo's Driving School. When can I come by?
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